Cholesterol infusion prevents heart attack

Written By Unknown on Senin, 05 November 2012 | 23.53

FOR heart attack victims fortunate enough to survive the initial emergency, there is a high risk they will succumb to a second fatal episode in the following weeks or months.

However, new Australian research shows an intravenous infusion of "good" cholesterol can reduce the chances of dying from a subsequent cardiac arrest.

An infusion of high density lipoprotein (HDL) can rapidly boost the body's ability to move cholesterol out of the plaque-clogged arteries that are responsible for heart attacks, a study by Australian biopharmaceutical company CSL Ltd has found.

CSL chief scientist, Dr Andrew Cuthbertson, says this new approach increases "reverse cholesterol transport", which sees the negative cholesterol expelled from the body via the liver.

"The way it does that is to suck the cholesterol out of those plaques in the walls in the arteries and calm them down and make them much less likely to burst and cause a second heart attack," Dr Cuthbertson told AAP.

"It shifts cholesterol out of plaques and back through the liver where you get rid of it."

He said the study's results were "very encouraging so far".

"The increase in reverse cholesterol transport is many, many fold higher following an infusion of this new drug."

Dr Cuthbertson said testing was continuing to determine a dosage that was effective and safe.

"Around the world many thousands of people have second heart attacks and die, so we're trying to provide a treatment that doesn't exist today."

However, he said if testing proved successful it would still be several years before the treatment was widely available.


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